… , pretreatment with novel survival protein inhibitors alone or in … Designed as a pan–Bcl-2
antagonist, BH3-M6 is the most … IAP antagonists either directly bind to IAP family proteins to …

… has previously been designed for the synthesis of these two … , Bucknam et al. accomplished
the stereoselective synthesis of … , as it is an IAP (inhibitor of apoptosis proteins) antagonist. …

… the presence of five peak compounds and thirteen anti-carcinogenic compounds. The
thirteen anti-carcinogenic compounds were docked with three target proteins (in silico analysis) …

… The unique structures containing an additional cyclopentane or cyclohexane annelated
to … In addition, by reducing 2–24d and following the mitsunobu process, novel transbis(tricyclo)-…

… in immune and bone cells could be a novel therapeutic approach to prevent or reduce bone
… These findings suggest that drugs, like chloroquine or cIAP antagonists (104), that inhibit …

… pairs) to rationally design inhibitors that target protein-protein interfaces. Our analysis was
… data of 10 new SIRPs, including novel target-partner protein combinations, such as Keap1/…